Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT) Following Adenovirus Vector COVID-19 Vaccination

Science Table, Covid-19 Advisory For Ontario

This Science Brief provides information for health care professionals about Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT), also known as Vaccine-Induced Prothrombotic Immune Thrombocytopenia (VIPIT) and Thrombotic Thrombocytopenia Syndrome (TTS). This is a rare adverse event following adenovirus vector COVID-19 vaccines, including the AstraZeneca/COVISHIELD and Janssen/Johnson & Johnson COVID-19 vaccines.

This brief describes the pathophysiology, presentation, diagnostic work-up and treatment of VITT.

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